3^rd International Conference and Exhibition on Traditional & Alternative Medicine August 03-05, 2015 Birmingham, UK

Biography:

Atsuyoshi Nishina has completed his PhD from Meiji University. He is the Professor of College of Science and Technology, Nihon University, Japan. He has published more than 40 papers in reputed journals.

Abstract:

While study of western drugs leading to dementia or depression has been conducted, many trials to prevent such diseases by herbal medicines have been also done. For instance, effects of ginkgo components or Yokukansan for dementia and Alzheimer’s disease, or effect of Chinese herbal medicines for depression have been reported. Herbal medicines are different from western medicines, because they can be prophylactically used by taking from healthy state in some cases. We focused on biological resources of Myanmar, where democratization has been advanced and accepts foreigners freely. In Myanmar, original traditional medicines have been used rather than Western medicines. Because the country was being isolated for a long term, constituents of Myanmar tradition medicines is uncertain. In the present study, we aimed to introduce new lead compounds for dementia or depression drugs by measuring effects of constituents of Myanmar tradition medicines in a neural model. Among 171 kind of extracts, methanol extract of Croton tiglium L. induced phosphorylation of ERK 1/2 as well as NGF, used as the positive reference compound while IC50 of cytotoxicity was >100 μg/mL. Not only ERK 1/2 but also JNK and p38 MAPK were phosphorylated by methanol extractof C. tiglium. Remarkable neurite outgrowth and expressions of Neurofilament-M were observed by addition of C. tiglium methanol extract at 10, 30, and 100 μg/mL for the medium of PC12 cells. Neurite outgrowth and phosphorylation of ERK 1/2 were down-regulated by addition of inhibitor of MEK (U0126), JNK, or p38MAPK whereas, neurite outgrowth and expressions of Neurofilament-M by NGF was inhibited only by U0126.

Biography:

Adrian Angel Inchauspe was certified as laparoscopic surgeon in La Plata, Buenos Aires, Aachen, Tubingen and Strasbourg Universities. Currently, he serves as Editorial Member and Reviewer in many foreign renowned journals. He participated as Chairman in several International Drug Discovery Congresses and in the 2nd International Conference and Exhibition on Traditional Medicine-2014 in Beijing, where he proposed the foundation of the World Union of Traditional Medicines. Since 2005, he serves as teacher in the Argentina Acupuncture Society and published his “Systematized Integration of Acupunctural Therapeutic Knowledge” book in 2014. He has been searching about Yongquan resuscitation in the last 28 years.

Abstract:

In the previous edition of the Traditional Medicine Conference held at Beijing, the actual possibility of the so called Five-Element Theory had, in fact, a precise foundation–which finds support in accurate propositions stated long ago by Alexandrian Greek Mathematician Euclid–was presented. Such assumptions may be said to derive from the most ancient formal science known to human beings: Geometry. In this opportunity, the latest advances of research in this specific field shall be presented by the author. These seem to verify that Chinese pentatonic music is not only related to the Five Movements but also that it finds a precise explanation in the Cylce of Fifhts proposed by the Mathematics genius Pythagoras. This new method, called Therapeutic Acupunctural Resonance calls upon both the Greek Mathematic hypotheses as well as upon principles derived from Chinese Medicine coinciding with Morphic Resonance, a concept first introduced by Prof. Rupert Shedrake in the early 1990s. The author shall also confront his work with several Chinese lines of research which deal with the propagated sensation (T´chi phenomenon) along meridians – such peculiar combination of both Oriental and Occidental knowledge – to which certain results he had can actually be assigned.

Biography:

Chang Jin Jung has completed his MSE from Kyung Hee University in South Korea. He is the Senior Researcher in Korea Institute of Oriental Medicine. He has published several papers for tongue diagnosis.

Abstract:

Atongue provides direct evidence for diagnosing one’s health condition based on its visual information, and it has been frequently used in Traditional East Asian Medicine clinics (TEAM). In particular, TEAM posits that the colour of tongue is highly related with digestive functions. In this study, the colour of tongue between the chronic dyspepsia patients and controlled healthy subjects were analyzed. The chronic dyspepsia patients with functional dyspepsia (n=23), gastroesophageal reflux disease (n=13), and gastritis (n=22) were recruited, and healthy subjects (n=11) were participated. Tongue images in profile view were acquired by using computerized tongue image acquisition system. The colours of the tongue body were extracted from the region in profile view of the tongue, where there was no coating. Colour differences in CIE L*a*b* colour space between the three sub-types of chronic dyspepsia patients and the healthy subjects were analyzes respectively by using multiple linear regression analysis with the factors groups, age, and sex. The variable b* was significantly lower in gastroesophageal reflux disease than that in healthy subjects (p=0.017). The variable a* was significantly lower in gastritis than that in healthy subjects (p=0.03). There was no significant difference between functional dyspepsia and healthy subjects. In gastroesophageal reflux disease, the colour of the tongue body seems to be changed to pale red colour. In gastritis, the colour of the tongue body seems to be changed to intense red colour. It is expected that the colour of the tongue body can be used for diagnosing digestive functions in healthcare.

Biography:

Rong Zhang has completed her PhD at Kyushu University in Japan and postdoctoral studies from University of Cincinnati in USA. She was an Associate Professor at Fudan University in China and She is a Faculty at Harvard Medical School and Children’s Hospital Boston. She has published more than 20 original research articles in peer-reviewed journals including Science, PNAS and Journal of Neuroscience. She regularly provides her professional opinions and reviews for some scientific Journals. She has won several awards or her academic achievement from China, Japan and USA.

Abstract:

Stress is anything in the external world that knocks you out of homeostatic balance. Chronic is the key word and stress hormones secreted into the brain can actually make you think more clearly over the short term. The student cramming for a final examinitially benefits from increasing oxygen delivery and nutrients to the brain. But by the six hours mark that student would be thinking less clearly, the neurons not working as well and the capacity for memory retrieval fading. Modern-day humans undergo chronic stress, for instance when they are stuck in traffic, when they are worried about paying the mortgage. These chronic stressors lead toillnesses such as anxiety, depression, ulcers, and heart disease. Fight or Flight, will bethe choices that our bodies react to stressful events. The hypothalamo-pituitary-adrenal (HPA) system is the major pathway in the mediation of the stress response. The hypothalamus releases corticotropin-releasing hormone (Crh) in response to stress, Crh acts on the pituitary gland, triggering the release of adreno-corticotropin (ACTH) into the bloodstream, which subsequently causes the hormonal end-product of the HPA-axis, corticosteroid release from the adrenal cortex. Crh-expressing neurons are mainly located in the paraventricular nucleus of hypothalamus (PVN) and amygdala. The role of PVNCrh in HPA axis regulation is indisputable, however, due to the lack of proper animal model, the role of PVNCrh inanxiety behavior regulation remains largely unknown. Our lab has successfully generated the Crhflox mice in which Crh exon 2 was chosen as the targeted exon because its removal would lead to excision of the entire coding region. Crhfl/fl mice were crossed with Sim1-Cre mice to delete the Crh mainly in PVN (PVNCrhKO). Mice with specific deletion of Crh from PVN have normal grown in terms of bodyweight, food intake and behaviors that were screened by Shirpa test.

Biography:

Zhao Dandan, MD, PhD is a Research Associate at Diabetes Research Center, Beijing University of Chinese Medicine, Beijing, China. The main researches include prevention and control of diabetes and its complications with traditional Chinese medicine based on Zang fu visceral-related theory. She has published about 20 papers, and was involved in edition of several books. She has participated in several research projects.

Abstract:

Given the substantial morbidity and mortality associated with type 2 diabetes (T2DM) and the fact that increasingly more people are suffering from T2DM and the associated disorders, there is greater pressure on clinical physicians and basic researchers seeking ways to prevent and treat T2DM, in which traditional Chinese medicine (TCM) plays a crucial role. Professor Sihua Gao’s diabetes research group have engaged in exploring pathogenesis, pattern differentiation, treating principles and methods of using TCM to treat T2DM, and lots of clinical experiences have been accumulated. As for the mechanism of diabetes in TCM, combination of internal and external pathogens is considered to be the reason for onset of T2DM, including poor innate essences, improper diet, unsuitable labor and rest, disordered seven emotion, and six external pathogens that induce kidney essence deficiency, liver qi stagnation, and impaired spleen and stomach function. Thus, we proposed a novel treating method for T2DM, which is characterized by regulating the function of liver, spleen and kidney, together with paying attention to treat the accompanying syndromes, whose rationality and safety were confirmed by the clinical trials, and the mechanism has been explained and verified in the recorded documents. Here, the basic theory, the scientific basis, the characteristics and the advantages of this method are fully discussed and analyzed. This novel idea of treating T2DM not only accords with two main features of Chinese medicine theory, holistic concept and syndrome differentiation, but also bases on understanding of diabetes from modern medicine perspective. This idea integrates Chinese medicine with modern medicine, enriches scientific basis of TCM, offer novel insights into understanding the mechanism, diagnosis, prevention and treatment as well as development of effective drugs for T2DM.

Biography:

Shanthi P has completed her MBBS and MD (Pathology) from the renowned Christian Medical College, Vellore and PhD from University of Madras. She has 33 years of teaching and research experience. She has guided a number of PhD students and MD students and published 103 research papers in peer reviewed journals. She has been the recipient of the prestigious ICRETT fellowship award of the UICC Geneva and the Academic Exchange fellowship of the Association of Commonwealth Universities. She has presented papers in various international/national conferences. Currently, she is the Director of University of Madras, Taramani Campus and Professor & Head, Department of Pathology of the same institute.

Abstract:

The siddha system of medicine is one of the oldest traditional systems of medicine, generated from Dravidian culture in Southern India. It is perhaps the foremost of all medical systems in the world and its definition is the conquest of death: “that which ensures prevention against mortality”. Semecarpus anacardium Linn. (Anacardiacae) commonly known as “marking nut” has high priority of use in the indigenous systems of medicine against various ailments. TLC, HPLC and HPTLC analyses have confirmed the presence of trihydroxyflavone, semecarpol, anacardoside and bhilawanols as chief constituents in the drug. Toxicity studies have revealed that the drug is non-toxic. With an increase in breast cancer incidences in India there is a surge in the screening of effective herbal drugs with minimal side effects. We have demonstrated the therapeutic effect of the drug SA in a DMBA induced experimental murine mammary carcinoma model as well as mammary carcinoma cell lines In vitro. The drug, by means of its strong antioxidant, anti-inflammatory, anti angiogenic, pro-apoptotic and membrane stabilizing properties, has a potent chemotherapeutic effect. SA restored deranged energy metabolism (to normal) in rats with mammary cancer and suppressed the expression of proteases, glycohydrolases, hypoxic and angiogenic factors. SA was also demonstrated to exhibit an immunomodulatory effect. This drug modulated the O glycosylation of mucin and down regulated the expression of matrix metalloproteinases, thereby preventing metastasis of cancer. Thus SA holds much promise as a therapeutic agent in breast cancer. Further evaluation in triple negative breast cancer would be a potential area of research.

Biography:

Abdul Matin has completed his PhD from Birkbeck, University of London and Postdoctoral Fellowship from School of Medicine, Southampton University Hospital, Southampton, United Kingdom. He has long-standing research interests includes the epidemiology and pathogenic mechanism of emerging parasitic diseases with special interest on role of blood-brain barrier in central nervous system infections. Using multi-disciplinary approach he is looking for potential novel synthesized compounds or nanoparticles or/and obtained from plants or insects to discover potential drug candidates for drug delivery system to alleviate the burden of life threatening infections. He was honored with a specialty award and prize titled “The Best Researcher in the UK” by Medical Research Society (MRS), one of the most prestigious research societies in the country; for his outstanding contribution in human brain research in 2007 at Royal College of Physicians, London, UK. He is currently Associate Professor and Head of Medical Lab Technology & Public Health Departments at University of Haripur, Pakistan. He has published more than 25 papers in reputed journals and has been serving as an Editorial Board Member and reviewer of reputed journals.

Abstract:

Acanthamoeba is an opportunistic protozoan pathogen and ubiquitous in nature. It plays a pivotal role in ecosystem and recognized to cause blinding keratitis and fatal granulomatous encephalitis involving the central nervous system with a very poor prognosis. This is due to limited availability of effective anti-Acanthamoeba drugs. The objective of the present study was to determine the efficacy of plant extracts derived by various methods (ethanol, methanol, acetone and aqueous) on Acanthamoeba binding and its cytotoxic effect on human brain microvascular endothelial cells (HCEC) In vitro. Using HCEC it was observed that Acanthamoeba (T4 genotype) exhibited binding (>85%) and cytotoxicity (>70%) to host cells. However, plant extracts remarkably inhibited more than 70% and 60% of Acanthamoeba binding and cytotoxicity to HCEC respectively. It is worth mentioning that methanolic extract showed maximum activity as compared to other extracts. It was further confirmed that extracts (ranging from 0.1 to 1.5mg/ml) exhibited amoebicidal effects, i.e. >50% of trophozoites were killed at maximum dose (1.5mg/ml) within one hour incubation. However the residual subpopulation remained static over longer incubations. Furthermore growth assay demonstrated crude extracts inhibited >50% Acanthamoeba numbers up to seven days. Our results confirmed that plant extracts has inhibitory effects on Acanthamoeba growth and viability. Overall, these findings revealed that tested plant extracts is inhibitory to Acanthamoeba properties associated with pathogenesis. To the best of our knowledge, our findings demonstrated for the first time that selected plant crude extracts exhibits inhibitory effects on biological properties of Acanthamoeba without any toxic effects on HCEC cells In vitro.

Biography:

Nouran A Aleyeidi completed the Saudi Board of Community Medicine. She has a publication on wet-cupping and hypertension. She is currently working in the Public Health Administration in the Ministry of Health, Jeddah, Saudi Arabia.

Abstract:

Practitioners who tend to do wet-cupping or “Hijama” to their patients, always be hesitant when they are dealing with anemic patients. Actually, they have a point, because wet cupping is a form of blood loss that might seem harmful for some cases. Nevertheless, there are very little researches studying the effect of wet-cupping on blood hemoglobin level. There are a number of case reports, mainly from Korea, of patients who performed wet-cupping and then developed anemia. In the other hand, there was a study done in Iran in 2009 by M. Mahdavi et al. where they performed wet-cupping on 56 healthy adult males, and there where no clinically significant difference between the hemoglobin level before and after the wet-cupping procedure. When we look deeply at those studies we can find some clear differences that most likely can be the reason behind the different effects on hemoglobin levels. Still we need more research in that area and we encourage all researchers who are doing or will do a research on wet-cupping to measure the CBC of their participants before and after the procedure to ensure the safety of their participants, and give us a better understanding of this possible side effect.

Biography:

Adamu Isa Imam has completed his PhD from Ahmadu Bello University, Zaria, Nigeria. He is currently a Lecturer at the Department of Human Physiology, Faculty of Medicine, Ahmadu Bello University, Nigeria. He has published more than 10 papers in reputed journals.

Abstract:

The present work was carried out to investigate the possible effects of ethyl acetate seed fraction of Nigella sativa on gastric ulcers and basal gastric secretions using the NSAID-induced model. Phytochemical screening revealed the presence of flavonoids, alkaloids, saponins, glucocinolates amongst others, whereas acute toxicity studies revealed a median lethal dose above 5000 mg/kg. The rats were grouped into 6 (n=5), with the extract fraction administered at 50, 100 and 200 mg/kg subcutaneously, followed by pyloric ligation with indomethacin and cimetidine used as the standard drug. For the mucosal integrity study, ulcer and preventive indices were analyzed, while volume of gastric juice, titratable acidity, acid output and pepsin concentration were assessed for basal gastric secretions. The three experimental doses of the extract at 50,100 and 200 mg/kg showed a dose-dependent decrease in both ulcer and preventive indices with the 200 mg/kg dose at 0.6 mm and 94% respectively. It also showed a significant (p<0.05) decrease in volume of gastric juice, titratable acidity, acid output and pepsin concentration in dose-dependent manner with the three experimental doses administered with the highest reduction at the 200 mg/kg dose. The results obtained suggest that this fraction down-regulated all those parameters which might be attributed to the presence of the phyto-constituents present in this fraction particularly the flavonoids, possibly through increase mucosal prostaglandin content, inhibition of histidine decarboxylase thereby decreasing histamine secretion and hydrochloric acid. Therefore, the extract fraction of this plant possesses gastro-protective activity further explaining the folkloric use of this plant in the therapy of peptic ulcer disease.

Biography:

Zoheir A Damanhouri is an Associate Professor of Pharmacology in the Faculty of Medicine, King Abdulaziz University, Saudi Arabia. He obtained his BSc from Lancaster University (UK), and his MSc and PhD from the University of Wales in 1988. He held various posts in the University as Director of King Fahad Medical Research Centre, Vice-Dean of the Faculty of Medicine, Chairman of the Pharmacology Dept., Dean of Graduate Studies in the University and later as Vice-President for Development from 2007 till 2013. He has over 35 publications in the field of pharmaceutical sciences as well as in Strategic Planning and Postgraduate Studies.

Abstract:

Nigella sativa (N. sativa) (Family Ranunculaceae) is a widely used medicinal plant throughout the world especially in Asia, Africa and many Middle Eastern countries. It is considered as one of the greatest forms of healing medicine. Extensive studies on N. sativa seeds have shown its potential pharmacological and therapeutic effects including antidiabetic, antihypertensive, diuretic, digestive, anticancer, antioxidant, analgesic, immunomodulator, antimicrobial, anti-inflammatory, spasmolytic, gastroprotective, hepatoprotective effects etc. However, there has been much concerned about herbal-drug interactions due to the increasingly reported adverse drug effects and poisoning associated with the use of herbal medicine. The effect of N. sativa extract on hepatic drug metabolism in the rat was investigated in our laboratory. Both in vivo and In vitro experiments were employed to investigate the possibility of induction and inhibition effects on drug metabolism. Acute dosing (0.56 g/Kg) with N. sativa extract to rats caused a significant increase in plasma level of dicoumarol. In vitro studies assessed in 10,000xg liver homogenates from treated animals showed a significant decrease in benzphetamine N-demythelation, dicoumarol oxidation and ethoxycoumarin O-deethylation activities compared to liver homogenates from control animals. In addition, N. sativa extracts was tested In vitro for its possible inhibitory effect on cDNA-expressed human cytochrome P450 3A4, 3A5, 2C9 and 3A7-mediated metabolism of marker substrates. The present study investigates and throws light on the possible interactions of N. sativa with conventional drugs.

Biography:

Jihye Kim has graduated from the College of Oriental Medicine, Sangji University and received a Master´s degree from the Department of Biofuntional Medicine and Diagnostics in 2013. She has joined the Korean Institute of Oriental Medicine as a Researcher in the same year. Her research interest is the prevention and diagnosis of chronic illnease using traditional Korean medicine approach. She has been working as an Expert of ISO/TC249 and the Project Leader of computerized tongue image analysis system.

Abstract:

Chronic Dyspepsia (CD) is one of the most common diseases worldwide. According to the theory of Traditional Medicine (TM), CD appears to have individual differences and therefore it can be subdivided into different pattern identification (PI). CD is mainly considered the Spleen Qi (SQ) deficiency PI. SQ deficiency PI is one of the most common pattern in TM clinics. However, no diagnostic tools such as a questionnaires or medical devices have been validated in clinical studies. This study was performed to determine the reliability and validity of the ‘Spleen Qi Deficiency Questionnaire (SQDQ)’ for the 60 patients with CD. All participants were evaluated by filling in SQDQ and analyzing them. The internal consistency and construct validity of SQDQ were assessed using all the dataset obtained in the current study. The SQDQ showed sufficient internal consistency. Four factors from the SQDQ were extracted through explanatory factor analysis. The percentage of explaiend variance was 65.1%. In the distribution of PI, 68.3% and 31.7% of the participants showed to have SQ and non-SQ groups respectively. The study compared the SQDQ scores between SQ and non-SQ groups. Significant differences in most of SQDQs’ items were observed between the SQ and the non-SQ groups. However, the ‘emaciation’, ‘tongue diagnosis’ and ‘pulse diagnosis’ illustrated no significant differences. The results suggest an alternative diagnostic approach to assess sub-patterns of CD. The proposed diagnostic method will help physicians classify patients into subgroups and the patients would benefit from more precise diagnosis and therapy.

Biography:

Prathamesh V Karpe received a Bachelor’s degree in Ayurveda Medicine & Surgery from Goa University and MS (Shalyatantra) from Maharashtra University of Health Science, Nasik, Maharashtra, India. He is currently practicing Ayurveda in Goa and working as honorary lecturer and consultant at Gomantak Ayurveda Mahavidyalaya & Research centre, Shiroda, Goa, India. He has presented various research papers at Ayurveda seminars in India and abroad.

Abstract:

Ayurveda understands the disease in terms of imbalanced doshas (bodily humors) and treatment aims at removing this unbalanced doshas out of the body and achieving a state of equilibrium in the body. To achieve this various purificatory procedures are told like Vaman (emesis), Virechan (purgation), Basti (medicated enema), Nasya (nasal medication) and Raktamokshana (bloodletting), these 5 procedures are collectively called as Panchakarma procedures. Raktamokshan includes various methods and commonly practiced are Siravedhan (vein-puncturing) and Jalaukavacharan (leech application). Raktamokshan is indicated in disorders of Pitta (fire/bile) and Rakta (blood) involvement, thus non healing wound which has imbalance of Pitta and Rakta can be well managed with Raktamokshana. It helps in preventing venous and capillary stasis and thus helps in proper venous drainage in the area of ulcer and thus improves its healing process. It also drains off excessive inflammatory mediators thus prevents swelling and pain and burning sensation instantly. Acharya Sushruta in Sushruta Samhita mentions specific veins to be punctured in particular diseases. This paper focuses on clinical aspect of Raktamokshana regarding its various techniques and methods and its efficacy in healing wounds.

Biography:

Md Obiedullah Baig has completed BUMS from Dr. MGR University, completed Post Graduation MD from Indian Institute of Alternative Medicine & Research Center, and then he completed Post Graduate Diploma in Herbal Bio-Technology in University of Madras. He has been awarded FCIP and he established Dr. Baig’s Unani Herbal Clinic in the year 2000. Since then he has published several research papers, articles in unani medicines & herbal research of various diseases. For the Unani & Herbal Research he got 2 International Awards and 5 National Awards.

Abstract:

Plants have been one of the most important sources of medicines. The screening and isolation of bioactive compounds from plants is increasing, as these compounds are much safer and less toxic than the chemically synthesized drugs. The antibacterial activity of the seeds of Psoralea corylifolia has already been documented. The extract of seeds has shown antibacterial activity against some of the oral bacterial species tested. Hence the study was done to evaluate the antibacterial effect of seeds of Psoralea corylifolia against some of the bacterial pathogens. The aqueous, chloroform and ethanolic extract of seeds of Psoralea corylifolia were tested for their activity against 10 different species. The extract showed activity against Shigella dysenteriae, Bacillus cereus, Salmonella typhi, Actinomyces viscosus and Vibrio cholerae whereas Escherichia coli, Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa and Enterococcus faecium were inhibited. Antibacterial effect of aqueous & chloroform extract of seeds were higher than the ethanolic extract against Staphylococcus aureus. The chloroform extract showed more inhibition against Pseudomonas aeruginosa, when compared to the inhibitory action of the ethanolic and aqueous extract of seeds. The ethanolic extract of seed was more active against Enterococcus faecium. The antimicrobial effect of Psoralea corylifolia seeds may be due to the presence of secondary metabolites. Hence further analysis of the compounds and their testing against micro-organisms would help to develop a new antimicrobial agent that may be of great importance.

Biography:

Ghazala Javed Mulla has completed her post graduation from University of Pune. She is the Head of the Department of Physiology at Z V M Unani Medical College, Maharashtra, India. She is teaching Physiology subject to under graduate students for last 16 years and Medical Genetics to post graduate students. She has three ongoing research projects to her credit sponsored by different Governmental agencies. She has published more than 10 papers in reputed journals and has been serving as an Editorial Board Member of repute. She has presented research paper at various international conferences in countries like Istanbul, Sri Lanka, Abu Dhabi and in India. She is the first author in India who wrote a book on cupping therapy.

Abstract:

Human classification or race can be described as a group of people who share similar and distinct physical characteristics. It is a social concept by which one group of human beings identifies and distinguish themselves from other group. The term race was initially confined to groups of people speaking common language later the term referred to national association. By 17th Century race is refer to physical (Phenotypical) traits. In Unani System of Medicine, ancient hakeems have identified ten phenotypic features and called them Ajnas-e-Ashra. Based on these features they classified human being into four groups viz., Damwi Mizaj, Balghami Mizaj, Safrawi Mizaj and Saudawi Mizaj. American psychologist William Sheldon (1898-1977) has also classified human beings into three types of personalities and termed them somatotypes. Sheldon’s somatotypes are also based on physical characteristics or physique. He has expressed them numerically and named them endomorphs, mesomorphs and ectomorphs. Sheldon’s body types can be assessed by ten anthropometric measurements. A pilot study has been conducted to explore the different Mizaj types and Somatotypes of the same subjects and to find out any relationship between these two methodologies and to point whether this relationship is merely a coincidence or a statistical correlation.

Biography:

Zhang-Jin Zhang is a Professor and an Associate Director (Clinical Affairs) of the School of Chinese Medicine of the University of Hong Kong (HKU). He received his Chinese medicine and Western medicine training and earned his PhD in Neuroscience in China. During 1994-2006, he continued his research work in psychopharmacology and clinical psychiatry at Vanderbilt University and Uniformed Services University of the Health Sciences (USUHS) in USA. His long-term research interest focuses on developing effective treatment strategies from herbal medicine and acupuncture for neuropsychiatric disorder, including depression, anxiety, dementia, and schizophrenia. He has authored over 90 research papers and 7 book chapters and delivered numerous seminars introducing herbal medicine and acupuncture for mental health and wellbeing. He has active clinical practice in Hong Kong with specialty in the use of acupuncture and Chinese medicine for neuropsychiatric problems.

Abstract:

Over the past decade, herbal medicine and acupuncture have been increasingly used to treat psychiatric diseases. Numerous herbal preparations, products and natural compounds have been tested for psychotropic potentials in laboratory and clinical settings. At the same time, acupuncture is well demonstrated to have benefits in treating anxiety, depression, insomnia, dementia and schizophrenia. In this symposium, several scientists will present their findings, including novel acupuncture therapy for depression and insomnia, and the use of herbal medicine for depression and sleep disturbance. This symposium also provides a platform with multidisciplinary professionals and research fields to share their respective knowledge and experiences and to develop new ideas in the use of herbal medicine and acupuncture to prevent and manage mental disease.

Biography:

Pei-Jing Rong is a Professor of the Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences. She received her Bachelor’s, Master and PhD degrees from Beijing University of Chinese Medicine and Hong Kong Baptist University, before she finished two-year Post doctoral visiting study at Faculty of Neurosciences in Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center. She has published more than 100 papers in reputed journals. She is one of the academic leaders in China Academy of Chinese Medical Sciences and the secretary general of Academic Committee for China Association of Acupuncture and Moxibustion.

Abstract:

Depression presents a significant burden to both patients and society. The treatment of Major Depressive Disorder (MDD) is far from satisfactory. One treatment that has emerged is vagus nerve stimulation (VNS), a FDA approved physical treatment for depressive disorders. However, the application of this intervention has been limited by the involvement of surgery and potential side effects. The aim of this study is to explore the feasibility of stimulating the superficial branches of the vagus nerve to treat MDD. To investigate the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) as a solo treatment for depression, the first cohort 91 patients only received taVNS for 12 weeks. In the second cohort 69 patients first received 4 weeks of sham taVNS, followed by 8 weeks of taVNS. All treatments were self-administered by the patients at home after they received training from the hospitals. The primary clinical outcome measurement was the 24-item Hamilton Depression Rating Scale measured at weeks 0, 4, 8 and 12. After four weeks of treatment, MDD patients in the taVNS group showed greater improvement than that of sham taVNS groups as indicated by both Hamilton score changes as well as rates of good responders. In addition, we also found that the clinical improvements continued until week 12. Our study demonstrated that taVNS is a promising, safe and cost-effective neuromodulation method for MDD treatment.

Biography:

Wing-Fai Yeung graduated from Hong Kong Baptist University and received Bachelor of Chinese Medicine & Bachelor of Science (Hons) in Biomedical Science degrees in 2004. He completed his PhD in the Department of Psychiatry, at the University of Hong Kong in 2010, and he worked as a Post-doctoral Fellow in the same year. He joined the School of Chinese Medicine as a Research Assistant Professor in 2014. His research interest is in the assessment and treatment of sleep disorder and major psychiatric disorders using traditional Chinese medicine approach.

Abstract:

Insomnia is a prevalent sleep disorder. It is very common that subjects with insomnia seek complementary and alternative therapies to improve their sleep. Traditional Chinese Medicine (TCM) interventions, including Chinese herbal medicine, acupuncture, acupressure, and auricular therapy, have been used for treating insomnia. Over the past decade, a large number of randomized controlled trials have been conducted to examine the efficacy of TCM interventions for treating insomnia. Recently, several systematic reviews have been performed to summarize the evidence on the efficacy of TCM interventions for insomnia; Chinese herbal medicine, acupuncture, acupressure, and auricular therapy have been reported to be more effective than placebo control, benzodiazepines, or other therapies in the short-term treatment of insomnia. However, the reviewed randomized controlled trials were generally of low methodological quality. Hence, the apparently promising results should be interpreted with caution. Most of the previous randomized controlled trials were rated as low quality trials due to: (1) improper description of the randomization method; (2) lack of blinding on either the subjects or the assessors; and (3) unclear report on the attrition data. These limitations may contribute biased results. Further clinical studies with rigorous methodology, such as precise diagnostic criteria, placebo-controlled and double-blind design, validated measures, and standardized adverse event monitoring are most warranted to accurately determine the benefits and risks of these TCM interventions for insomnia.

Biography:

Hideto Shinno is Graduated from Hiroshima University School of Medicine (MD) and (PhD). He received National License of Medical Doctor. Currently he is working as Professor at Department of Liaison Psychiatry, Kagawa University School of Medicine, Kagawa, Japan.

Abstract:

Previous studies of sleep in the elderly subjects have revealed a decrease in the amount of slow-wave sleep, and rapid eye movement (REM) sleep, reduction of nocturnal melatonin secretion, and advancement of the sleep phase. In addition, periodic limb movements during sleep (PLMs) are commonly observed in the elderly and often cause sleep disturbances. PLMs are generally considered to produce sleep fragmentation by provoking arousals. Recent studies have demonstrated the effect of YKS on the sleep architecture in the elderly patients who complained subjective sleep disturbances. After treated with YKS, polysomnography studies revealed increases in total sleep time, sleep efficiency and stage II sleep. Decreases in electroencephalogical arousals and PLMs were also reported. YKS has reported to be effective and well tolerated in the elderly patients who complained of sleep disturbances. Yokukan-San (YKS: Tsumura Co. Ltd. Japan), a traditional herbal prescription, was developed as a remedy for restlessness and agitation. YKS contains several herbal medicines (Atractylodis lanceae rhizoma, Hoelen, Cnidii rhizoma, Angelicae radix, Bupleuri radix, Glycyrrhizae radix, and Uncariae ramulus et uncus). Angelicae radix, an important component of YKS, is known to affect dopamine, γ-aminobutyric acid (GABA), and serotonin receptors. In aged rats, YKS has been reported to improve the decreased level of dopamine in the prefrontal cortex. YKS has been indicated to ameliorate age-related impairments of working memory via the dopaminergic system. Therefore, YKS may be effective for improving the decreased dopaminergic neuronal function that is responsible for the emergence of PLMs and restless legs syndrome (RLS). Animal studies have demonstrated that YKS exhibits an anxiolytic effect mediated by GABA receptors. These pharmacological actions on dopaminergic and GABAergic systems may be beneficial for reducing PLM and treating sleep disturbances including RLS.

Biography:

Sungwook Chae has earned his PhD from Natural Products Research Institute at Seoul National University, South Korea and Postdoctoral studies from Massachusetts Institute of Technology, USA. He is Senior Researcher of KM based herbal drug research group. He has published more than 40 papers in reputed journals regarding antioxidant and skin research field.

Abstract:

Due to development of health science and medicine, life expectancy has increased. Therefore, more people have been showing dermatological concerns in recent years. Chronic exposure of human skin to solar ultraviolet (UV) radiation causes photoaging which accelerates the visible ageing of skin together with intrinsic aging. Many studies showed that naturally occurring compounds are known to have anti-photo aging effects via oral administration. The market for cosmetics that are natural is converging with the growth of foods and nutritional products catering to “beauty from within” to create great opportunities for anti-wrinkle treatment. And topical treatment like cosmetics is also important because of their pharmaceutical benefits. Our study started from this concept; these two types of topical cosmetics and nutricosmetic need to be combined to work in a complementary and alternative way, which replenish the body’s own collagen by providing essential sources and enhancing epidermal function. Our lead material (KIOM-HB10) used in this study showed anti-wrinkle properties in terms of skin thickness, and changes in collagen fibers in HR-1 hairless mice. In the in vivo results, UVB-induced mean length and mean depth of skin wrinkle, epidermal thickening, and damage to collagen fiber were restored by oral administration of KIOM-HB10. In vitro results showed that KIOM-HB10 inhibited UVB-induced damage in HaCaT human keratinocyte by lowering the level of matrix metalloproteinase (MMPs).

Biography:

Prem P Rai (PhD) teaches at the University of Papua New Guinea, School of Medicine and Health Sciences. He specializes in Pharmacognosy and Traditional Medicine. He also heads the traditional medicine program of the National Department of Health in Papua New Guinea. He has published more than 80 papers in reputed journals and authored number of technical books including one on medicinal plants in Papua New Guinea, published by the World Health Organization. He serves as an Advisor and Member on Editorial Board of number of local and international scientific journals.

Abstract:

Papua New Guinea (PNG) is one of the most biologically diverse places on earth. It is estimated that 15,000 to 20,000 individual species of vascular plants may be found in PNG; most of these are endemic. A rich tradition of medicinal plants use exists in PNG with well over 50% of the population relying exclusively on traditional herbal medicine for health care. The government policy aims to incorporate traditional medicine in the primary health care system. Consequently, scientific investigation of commonly used medicinal plants has been undertaken through various national and international research initiatives. Traditional medical knowledge has been largely oral, and one of the early tasks was to undertake a systematic and comprehensive documentation of medicinal plants use, practiced in communities across the nation. This work has lead to establishment of traditional medicine database with detailed account of over 4000 traditional preparations from approximately 450 plant species. Phytochemical analysis of medicinal plants, determination of antibacterial activities of herbs used in respiratory and related conditions, standardization and validation of traditional herbal medicines employing both chemical and pharmacological approaches and a broad drug discovery program from PNG natural materials are the major thrust of these researches. PNG experiences HIV epidemic, and in our recent works the question that is being addressed is whether commonly used medicinal plants in PNG interact with HIV to either suppress the infection or to exacerbate it. The findings indicate that plants that inhibit HIV in the laboratory have the potential to contribute to successful management of infection and may be useful to people living with HIV (PLHIV) who have irregular access to anti-retroviral therapy (ART). Conversely, plants that activate latent HIV in the laboratory have the potential to shorten the period of disease latency in asymptomatic PLHIV and therefore pose a potential hazard. This presentation will attempt to highlight researches over the last two decades on PNG traditional medicine and provide direction for its inclusion in PNG national health system.

Biography:

Gong has completed his PhD in Gastroenterology from 2nd Military Medical University of Shanghai in the year 1997. Currently he is working as specialist in the Department of Oncology, Nanjing 1st Hospital, Nanjing Medical University, China. He has published more than 40 scientific papers in various national and international journals and a reviewer for reputed journals. Apart from medical oncology, his area of interest is Chinese traditional medicine therapy of hepatic cell carcinoma carcinoma.

Abstract:

Objective is to observe the curative effect of Chinese herbal decoction of Runfei combined with hormone and antibiotic in treating radiation pneumonia (RP) of oesophageal carcinoma. A 56-year-old male underwent surgery for cancer of the upper easophagus (T3N2M0) in Sep. 2014; following post-surgery adjuvant radiotherapy of three dimensional conformal radiotherapies were administered. Two months later, severe pneumonia had been found by chest X-ray and CT imaging, he received the treatment of hormone and antibiotic. In the meantime, we administered Chinese herbal medicine (Fei Decoction, mixed a variety of effective herbal components) to help him to recover from the poor condition. After taking the Chinese herbs for 2 weeks, the diffuse patchy shadows and ground glass appearance on chest X-ray dramatically decreased, with the result to the normal range, and the patient felt free from the complaint of pulmanory and cardiac discomfort. The quality of life has been greatly improved; we managed to have prolonged the PFS (Progression-Free-Survival) and TTP (Time-to-Progression) from the onset to date. In the course of this combined treatment, we showed that Chinese herbal medicine played an important role in the therapy of oeasophageal carcinoma. Chinese herbs might be an additional choice with its better benefits and tolerability in the treatment of radiation pneumonia (RP) of oesophageal carcinoma.

Biography:

Susilorini has completed her Master of Medical Science from Magister of Biomedic of Diponegoro University and Pathology Anatomy Residency from Medical faculty of Diponegoro University. She is a pathologist and staff of Departement Pathology Anatomy of Medical faculty of Sultan Agung Islamic University and Sultan Agung Islamic hospital. Her research foccused in the prophetic medicine.

Abstract:

Multiflora honey contains poliphenol especially quercetin that was shown to have antioxidant, anti inflammation and anti proliferating effect, which potentially decreased damage of renal tissue caused by diabetic nephropathy. We investigate the effect of multiflora honey on VEGF expression and glomerular tuft area in renal tissue of STZ-induced Sprague- dawley rats. It was a randomized post test only control group, animal experimental study. 20 rats were divided into 4 groups, hyperglycemic control (K) group; and treatment group (P1= honey 0.33 g/kgBW/day, P2= honey 1 g/kgBW/day and P3= honey 10 g/kgBW/day). Postpandrial Blood glucose were measured after 2 days post injection. All rats were terminated at 15th days. The VEGF expression and glomerular-tuft area of renal tissue were measured by Allred score and Software OLIVIA. VEGF expression was analyzed by Kruskal Wallis test, Mann Whitney U test and Spearman correlation test. Glomerular-tuft area was analyzed by One-way ANOVA, post-hoc LSD test and Pearson correlation test. The expression levels of VEGF in renal tissue of P1and P2, groups are significantly different than that of K group (p= 0.0001), no significant dose - effect relationship of VEGF expression. The glomerular tuft areas in renal tissue are significantly different between groups. There was a significant dose-effect relationship of glomerular tuft area (r= - 0.291). All doses of multiflora honey decreased glomerular tuft area. Only dose 0.33 and 1 g/kgBw/day could decrease VEGF expression.

Biography:

Yu-Chiang Hung is currently working in Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital and School of Traditional Chinese Medicine, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Abstract:

Background: Traditional Chinese medicine (TCM) is the most commonly used alternative therapy in children with asthma, especially in the Chinese community. This study aimed to investigate the effects of the government sponsored Outpatient’s Healthcare Quality Improvement (OHQI) project with integrated TCM treatment on childhood asthma. Methods: This study used the Longitudinal Health Insurance Database 2000, which is a part of the Taiwan National Health Insurance Research Database (NHIRD). Children with diagnosed asthma and aged under 15 years from 2006–2010 were enrolled. They were collated into 3 groups: (1) subjects treated with non-TCM; (2) subjects treated with single TCM; and (3) subjects treated with integrative OHQI TCM. The medical visits and the cost of treatment paid by the Bureau of National Health Insurance (BNHI) to the outpatient, emergency room, and inpatient departments were evaluated for the study subjects within 1 year of the first asthma diagnosis during the study period. Results: Fifteen multi-hospitals, including 7 medical centers, and 35 TCM physicians participated in OHQI during the study period. A total of 12850 children from the NHIRD database were enrolled in this study, and divided as follows: 12435 children in non-TCM group, 406 children in single TCM group, and 9 children in integrative OHQI TCM group. Although the total medical cost paid by the BNHI per patient in the integrative OHQI TCM group was greater than that in the non-OHQI groups, the patients in the integrative OHQI TCM group exhibited greater therapeutic effects, and did not require ER visits or hospitalization. In addition, ER visits and hospitalization among patients who received a combination of conventional therapy with integrated TCM were lower than those among patients who underwent conventional therapy alone or single TCM treatment. Conclusions: Asthmatic children at partly controlled level under conventional therapy may benefit from adjuvant treatment with integrated TCM.

Biography:

Mohammad A Randhawa graduated from King Edward Medical College, Lahore, in 1973 and completed his Masters from University of Punjab in 1977. Then after, he was deputed for Postgraduate training in Clinical Pharmacology to St Bartholomew’s Hospital, London, UK. On his return to Pakistan, he obtained PhD degree from Quaid-i-Azam University, Islamabad. Currently, he is Professor and Head of the Department of Pharmacology, College of Medicine, Northern Border University, Arar. He has published more than 40 papers in reputed scientific journals and has reviewed numerous research projects and manuscripts, mostly related to membrane transport of drugs and N. sativa (Black seed).

Abstract:

Nigella sativa (N. sativa) seed is commonly known as ‘Black Seed’ has been an important natural remedy for many ailments for centuries in traditional systems of medicine. N. sativa contains many active components, including: thymoquinone, thymohydroquinone, dithymoquinone, thymol, carvacrol, nigellimine, nigellicine, nigellidine and alphahederin. In addition, N. sativa seed is reported to possess numerous pharmacological effects: immune stimulation, anti-inflammatory, antioxidant, anticancer, hypoglycemic, antihypertensive, antiasthmatic, antimicrobial and antiparasitic, etc. Some authors have reviewed pharmacotherapeutic activities of N. sativa in general, but their dermatological applications are not sufficiently described in these reviews. Skin is immediately exposed to numerous noxious stimuli: Microbial infections, trauma, chronic irritation and extremes of temperature and performs many physiological functions, to mention is its involvement in immune mechanisms. Literature search revealed a lot of published articles regarding effects and applications of N. sativa related to skin, e.g. ether extract of N. sativa was reported to possess inhibitory effect on Gram-positive bacteria (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aerogenosa), including their multidrug resistant strains. Ether extract of N. sativa and its active principles (thymoquinone, thymohydroquinone and thymol) were demonstrated to have antifungal activity against clinical isolates of important genera of dermatophytes: Trichophyton, Epidermophyton and Microsporum. Similarly, N. sativa extract/thymoquinone was found to be beneficial in acne, eczema, psoriasis and squamous cell carcinoma. The present work is intended to review the scientific knowledge about this important natural herb pertaining to skin problems. It is hoped that our effort would be of interest to skin specialists, general physicians, scientists and the public.

Biography:

Isa Adamu Imam is currently working as Faculty of Medicine, Department of human Physiology, Ahmadu Bello University, Zaria, Nigeria.

Abstract:

Cordia africana (Boraginaceae) is a tree used in traditional medicine to treat inflammatory related conditions and infectious diseases. This study was undertaken with the objectives of establishing the scavenging effect of extracts and fractions of Cordia Africana on the mediator of inflammation Lipoxygenases (LOX), and some non-biological free radicals such as 2,2-diphenyl-1- picrylhydrazyl (DPPH), the [2, 2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)] (ABTS) radicals and the Ferric ion reducing antioxidant power (FRAP). Antimicrobial activities, total phenolics/flavonoids and cytotoxicity of extracts of Cordia Africana were also evaluated. Extracts were obtained by maceration. Anti-inflammatory activity was determined using a LOX-inhibitor screening assay kit according to the manufacturer’s instructions. A broth serial micro dilution method was used to determine the minimum inhibitory concentration (MIC) against, Gram-positive and Gram-negative bacteria. The antioxidant activity was determined using free-radical-scavenging assays, and the 3-(4,5-dimethylthiazolyl-2)-2,5- diphenyltetrazolium bromide reduction assay was used for cytotoxicity. All the extracts of C. africana inhibited LOX enzyme. The most active being the hexane extract of the leaves with IC50 value of 190±0.9 μg/ml. With the exception of the Methanol extract of bark of C. africana, all extracts had excellent to weak antimicrobial activity (MICs ranging from 16 to 1024 μg/ml) bacteria. All the extracts had free-radical scavenging activity (IC50 ranging from 5.20 to 314.30 μg/ml). There was a positive correlation between the antioxidant activity and the total flavonoid and total phenolic contents of Cordia africana. The cytotoxicity on Vero cells was reasonable to low with LC50 values ranging between 56.23 and 800 μg/ml. Our results support the use of C. africana leaves in traditional medicine to treat inflammatory related conditions and infectious diseases.

Biography:

Fei Wang is a PhD Acupuncturist and Traditional Chinese Medicine Doctor. He is a Member of IPTI and Lecturer at The College of Naturopathic Medicine. He successfully completed a 3 year PhD of Acupuncture in Shanghai University of Traditional Chinese Medicine in 1998. He graduated from Henan College of TCM in China in 1995 with a Bachelor’s degree of Traditional Chinese Medicine and Master of Acupuncture. As a highly experienced acupuncturist and traditional Chinese medicine doctor, as well as a qualified doctor in China, he worked at the renowned Ruijin Hospital (Shanghai) and The Institute of Chinese Medicine (London), and was once commissioned by the Saudi Royalty. He has been actively promoting acupuncture and traditional Chinese medicine through clinical practice, research and lecture in China and in Europe since 1992. In addition to his specialty of traditional acupuncture and traditional Chinese medicine, he also does cupping, moxibustion and deep-tissue massage, in combination or separately.

Abstract:

Nowadays, few people would argue about the effectiveness of acupuncture, the ancient healing art in treating certain illness. However, the mechanism of acupuncture remains in controversy. For the first time, the author makes his hypothesis public, based on his decades of clinical practice experience and observation. He believes acupuncture works through stimulation to nervous-immune system, the effect must be very similar to vaccination. In another words, acupuncture treatments create pseudo injuries to a living human body in an elaborately controlled manner in order to wake up the living body’s immunity system, or human being’s natural healing capability. It is a “vaccination” for disease prevention, a self-healing “exercise” designated for training on immunity.

Biography:

Seethalakshmy A expertised in Rajayoga Power Trranscendental Meditation Society, Malaysia and she is practising the techniques of meditation, healing, sub conscious mind programming, negativity remover and Divine Shield for the past 7 Years. she has been empowered with Kundalini awakening and the art of Pranic Energy Retention by the World Leading Siddha of Yoga, Divine Wisdom and Meditation Practice.

Abstract:

Rajayoga is an ancient practice, popularised by the Indian Sage Pathanjali, which comprises of 8 limbs, namely Yama (Abstaining from unhealthy habits), Niyama (Adhering to healthy habits), Asana (postures for meditation; also includes yoga practices), Pranayama (Breathing Technique), Prathiyahara (The attempt to control the mind), Dharana (The ability to control the mind), Dhiyana (Meditation) and Samaddhi (Superconsciousness). Rajayoga requires the practitioner to retain within one’s self the life force called the Prana through the practice of Pranayama, which is the key to optimal health and longevity. Coupled with meditation, one actually activates all the energy centres in one’s body (called the Chakra), with which constant practice leads to perfect health and disease-free state. We would like to take the opportunity to describe the state-of-the-art Rajayoga technique tailored for current era by our Guru, the world renowned Siddha, Yoga Jnana Sitthar Om Sri Rajayoga Guru (Sri Dr. V. Balakrishnan), who resides in Malaysia and undertakes to teach people from all over the world; the ancient practice of Rajayoga in a simplified and easy-to-follow manner. Real life testimonies of practitioners who have used this technique for health and seen tremendous changes will also be presented.

Biography:

Chun-En is a Medical Doctor of Chinese Medicine, Resident of Acupuncture Department at Kaohsiung Chang Gung Memorial Hospital, Taiwan. She is trained as a Medical Doctor at Kaohsiung Chang Gung Memorial Hospital with experience acupuncture and a passion for CAM studies. Since 2011, she has worked as a CAM resident with a major in acupuncture. She has been a member of Chinese Medical Association of Acupuncture (CMAA) since 2014, and she obtained the documentation of subspecialty in Chinese Dermatology. Her research topics focus on CAM in treating chronic tinnitus, modern medical devices for meridian analysis such as Ryodoraku, and the epidemiologic characteristics of CAM nursing in Taiwan. Her recent research interest is the connection of metabonomics with CAM syndrome differentiation and treatment.

Abstract:

Objective: We sought to investigate the effect of acupuncture treatment on tinnitus. Design: Retrospectively observational analysis of clinical practice. Setting: Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Subjects: Patients who reported tinnitus as their primary complaint at their first visit within a 27-month consecutive period (March 2010 to June 2012) were recruited into the study. The number of cases during the study period determined the sample size. Thirty-nine patients met the eligibility criteria. Ten consecutive patients were collected from otolaryngology department for control. Total forty-nine patients enrolled for the study. Interventions: Patients received acupuncture treatment by using single unilateral acupoint Ting-gong (SI19). Outcome Measures: Questionnaires including the tinnitus handicap inventory (THI) and tinnitus severity index (TSI) were recorded, those applied before and after the acupuncture treatment for recognizing the patients situation practically. Any use of remedies and Chinese herbal medicines was recorded. Results: The reduction of THI score was statistically significant from the baseline to the end of the treatment. The observed reduction score was more consistent between women aged 41 to 60 years. Acupuncture treatment seemed to improve the sleep quality of patients. No adverse reactions or complications were encountered resulting from the acupuncture procedure but sourness complaints occasionally. Conclusions: We observed that acupuncture therapy might improve the general well-being and relieve sleep disturbance associated tinnitus. No subjective hearing acuity improvement was observed in laboratory data, possibly due to small sample size. We suggest that further studies to explore the efficacy of acupuncture therapy in relieving of sleep disturbance associated tinnitus to be merited.

Biography:

Wen-Long Hu is the Vice Director, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, an Assistant Professor at Fooyin University, Kaohsiung Medical University, and Chang Gung University. He is invited to write a chapter entitled “Acupuncture for Disorders of Consciousness” in Acupuncture - Clinical Practice, Particular Technics and Special Issues (2011) and one entitled “Explore Laser Acupuncture’s Role” in Acupuncture in Modern Medicine (2013). Prior to his current position, he was Chief of Division of Acupuncture at Kaohsiung Medical University Hospital. He has the experiences of clinical practice in low level laser therapy (LLLT) for 20 years and in acupuncture for 25 years. He is invited speaker for lectures in LLLT at many symposiums held by some medical associations. Recently, he is invited to instruct physicians to practice LLLT in workshops. He also involves researches in LLLT, e.g. obesity, metabolic syndrome, stroke, dementia, Parkinsonism, myofascial pain, arthralgia, radiculopathy, etc.

Abstract:

Objective: To determine the therapeutic effect of laser acupuncture in pain management. Methods: This study includes five cases of intractable pain. Each subject was treated once per day (acute pain) or three times per week (chronic pain) with gallium aluminum arsenide (GaAlAs) laser (Handylaser Trion, RJ-Laser; Reimers & Janssen GmbH, Winden, Germany; Table 1& 2) therapy. The instrument was used to deliver 0.375 J of energy sequentially to each acupoint or 3 J to each Ashi point, for durations of 5 s or 40 s, respectively. The pain visual analog scale (VAS) and related disability of the patients were evaluated throughout the treatment by WLH. Clinical features: Case1: A 59-year-old man had been unable to chew hard food (e.g. peanuts, etc.) for many years. He complained of jaw pain at rest (VAS = 9) and restriction of mandibular movement over the previous 2 months.. Case 2: A 55-year-old woman complained of pain in the left buttock radiating to her left foot. Case 3: A 50-year-old woman complained of pain, swelling, redness, and heat in her left knee with limited range of motion, which she had experienced since undergoing total knee replacement (TKR) for osteoarthritis 3 months previously. Case 4: We treated an 82-year-old woman with a history of various diseases, including chronic hepatitis C, mild C1/2 canal narrowing, bilateral renal parenchyma disease, osteoporosis, and an old T10 compression fracture. The patient had suffered back pain for 1 week. Case 5: A 47-year-old man had suffered left chest pain caused by a traffic accident 5 days previously.

Biography:

Xiaochun Yu, BMed, MMed & PhD is a Professor and Deputy Director of Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Doctoral tutor. His research interest is to explore the mechanism of acupuncture and moxibustion and acupoint specificity as well as joint administration of acupuncture and drugs. So far totally 7 research projects including National Basic Research Programs of China are/were granted by Ministry of Science and Technology of China, National Natural Science Foundation of China and Natural Science Foundation of Beijing (as the Principal Investigator), and more than 90 articles in total were published in SCI and Chinese journals.

Abstract:

Our previous study showed that the cardiac arrhythmias induced by myocardial ischemia and reperfusion were attenuated by the pretreatment of acupuncture. The present study explored further whether intracellular Ca2+ ([Ca2+]i) and connexin 43 (Cx43) are involved in the mediation of the anti-arrhythmic effect of electro-acupuncture (EA) pretreatment in the rats subjected to simulative global ischemia and reperfusion (SGIR). SGIR was made in the isolated heart by a lowflow perfusion followed by restoration of the flow to the control level. Adult rats were randomly divided into four groups, namely, normal control group, SGIR group, EA group and EA plus 18 beta-glycyrrhetinic acid (EAG) group. For EA pretreatment, bilateral Neiguan acupoints (PC6) of the rats were stimulated for 30 min once a day for 3 consecutive days. Cx43 antagonist was given to the rats in EAG group 30 minutes before the pretreatment of EA. The resting [Ca2+]i concentration, calcium oscillation, the contents of total Cx43 and non-phosphorylated Cx43 and arrhythmia score were compared among different groups. The results showed that EA pretreatment could produce anti-arrhythmic effect in the rats subjected to SGIR. The anti-arrhythmic effect of EA pretreatment may be due at least partly to the inhibition of SGIR-induced calcium overload and [Ca2+]i oscillations, reduction of non-phosphorylated Cx43 and the enhancement of the corresponding phosphorylated Cx43 in the cardiac cells.

Biography:

Abstract:

This study was undertaken to evaluate the antioxidant effect for the aqueous extract of Psidium guajava unripe fruit peel. Two different methods for extraction were used; microwave and the conventional soxhlet extraction methods for the correlation of their antioxidant effect with their chemical profile. Previous studies was undertaken to evaluate the hypoglycemic, hypolipidaemic and antimicrobial effects, where significant differences were observed between the two extracts. That was followed by HPLC-MSMS analysis for their phenolic content. As expected, the two extracts showed variations in their phenolic profile, which were used to justify the differences in their pharmacological effects.

Biography:

Prathamesh V Karpe has a Bachelors degree in Ayurveda Medicine & Surgery from Goa University and MS (Shalyatantra) from Maharashtra University of Health Science, Nasik, Maharashtra, India. He is currently practicing Ayurveda in Goa and attached as honorary Lecturer and consultant at Gomantak Ayurveda Mahavidyalaya & Research centre, Shiroda Goa- India and Ayurclinic-Goa, Baga-Goa India. He has presented various research papers at Ayurveda seminars in India and abroad.

Abstract:

Urolithiasis is the stone formed in urinary tract (kidney, ureter, bladder and urethra). Synonym for Urolithiasis is urine stone/calculi. In Ayurveda it is known as Ashmari which means calculi or stone and its small powder like pieces are known as Sharkara or Sikatai.e. gravels. In Sushruta Samhita, Sushrutacharya explains the two process of stone formation. One is by the stagnation and super saturation of the urine and other by crystallization of the crystalloids in the urine. Charakacharya in Charka Samhita more specifically explains the process of gall bladder stone formation. Various herbal formulations are mentioned in classical texts and are found effective till today. Specific group of drugs are mentioned on basis of type of stone on its Doshas combinations. Urine stones are classified on basis of doshas – Vata, Pitta, Kapha etc and treatment is mentioned accordingly. The drugs like Varuna, Pashanabheda, Troonapanchamoola, Gokshura, Punarnava, Apamargakshar etc. are advised to be administered either in form of decoctions, fermented solutions, powder, cold infusions etc or in form of dietary products like cooked rice, gruel etc. Stones which are too large and not responding to medicinal treatment should be extracted surgically and for this Sushruta had mentioned perineal approach to remove the stone from the bladder. This paper will deal with the literature and clinical aspect of the Urolithiasis and its management in Ayurveda.

Biography:

Suzanne M Enoh-Arthur current study supports folklore identification of the Moringacaeae family in ancient and current African Traditional Food and Medicine Systems to promote its role in primary healthcare settings alongside developing Moringa oleifera (Lam). tree crop cultivation on degraded household farm lands to increase yields of desirable local food crops whilst ensuring value added natural resources for household nutrition, clinical heath studies, apprenticeship, alternative income generation and small-scale entrepreneurship development in West (Ghana) and Central (Cameroon) Africa.

Abstract:

Many countries are seeking ways of making best use of local natural resources. Hippocrates once said “let medicine be your food and food your medicine”. Hence the need to support African homes, institutions and local communities with domestication of natural resources for their food and medicine values. This is in line with a WHO resolution of 2000, which recognises and recommends the acceleration of local production of traditional medicinal plants. Many traditional medicinal properties of such plants like Moringa oleifera (Lam.) of the Moringaceae family are confirmed by studies that validate ethnobotanical herbal food and medicinal use practices of indigenous people worldwide. This study uses a Ghana perspective in the Volta region, Hohoe district, village of TafiAbuife, observing two groups of households belonging to local farmworkers who identified ‘yevu-ti’, (the Ewe name of moringa, meaning the white man’s tree). The research examines if people had knowledge and access to sustainable sources of medicinal plants for food and medicine, would they use it for healing? Hence the hypothesis ‘if people had healing knowledge and access to Moringa as herbal food and medicine then the latter will use Moringa as food and medicine for healing’. This was tested in different households and evidence used to support current domiciliary health care for farmworkers in an African village. The recruitment of participants by announcementin the village of Tafi Abuife, where baseline information suggested local people had access to Moringa trees planted as live fence in their localities but they had no knowledge of anycurrent domiciliary use of Moringa as herbal food and medicine. Moringa tree crop production in household gardens and farms with the processing of herbal food and medicines was completed over five years involving participants in group1 [Tafi Abuife local community residents (n=208)] and group 2 [workers of Bomarts Farm (n= 67)]. Face to face discussions, semi structured questionnaires and household analysis were used for data collection. From observations contrasted with baseline information there was evidence of herbal food and medicine use in some households in the studied locality. Over 38.9% of households in group 1 and 58.2% in group 2 responded positively to currently using Moringa in domiciliary herbal food and medicine healing practices, with a direct impact on over 30% children living in such households from an exploratory health survey completed in 2010. Both groups cited ownership of sustainable access to Moringa trees in household gardens and farms which also brought income from sale of raw and value added Moringa leaf and seeds. Peer-to peer and common initiative groups’ stimulated discussions within and between groups at home, and at work sharing information about domiciliary food and medicine, healing practices whilst learning from one another. A change in practice from single live fence Moringa trees to tree crop production has supported the acceleration of sustainable access and ownership to Moringa natural resource for food and medicine healing practices.

Biography:

Ilana Berlowitz is investigating traditional Amazonian medicine and its therapeutic applications in the context of substance use disorders in the pursuit of a PhD in Psychology at the unit of Clinical and Health Psychology at the University of Fribourg, Switzerland. She is conducting this research in collaboration with the Takiwasi Center for addiction treatment and rehabilitation in Tarapoto (Peru), the University of Neuchatel (Switzerland) and the University of Zurich/ETH (Switzerland). Her Doctoral project is funded by a Doc.CH Bursary of the Swiss National Science Foundation.

Abstract:

Traditional medicines take an increasingly important role in western health care systems, specifically for chronic problems that resist common treatment methods, such as substance use disorders. In this context, traditional Amazonian medicine has been applied by the Peruvian Takiwasi Center for Addiction Treatment and Rehabilitation since the 1990s, combining such traditional treatments from the Amazon with conventional western psychotherapeutic modules. We employed a multimodal research approach to assess therapeutic potentials of this treatment, namely by asking practitioners of traditional Amazonian medicine about their conceptions of substance use, disorders and about its treatment, as well as by quantitatively assessing therapeutic effects and mechanisms on a sample of substance use patients getting treated at the Takiwasi Center. First results of the qualitative study concerning Amazonian conceptions and treatment of substance use disorders will be presented. We collected data from a sample of 13 practitioners of traditional Amazonian medicine that have extensive experience with substance use patients. Interviews yielded arrange of different views with regards to the conceptual understanding of substance use disorders but tended to converge on the Amazonian methods that can alleviate such ailments. A majority of practitioners consider particularly the so called Dietas, -dietary retreats in the rainforest using plant remedies and specific nutritional/behavioral restrictions - an efficacious traditional Amazonian method for treating substance use problems.

Biography:

Lucia Maria N F de Albuquerque is specializing in floral therapy. She is a member of the group of complementary and alternative therapies studies from the Nursing School University of Sao Paulo.

Abstract:

Among people who live in slums there is a big number of children and teenagers that live in a constant risky situation. The facts of risk are those that, if present, inscrease the possibility of a child to develop an emotional or behavioural disorder. The aim of this research is to analyze the results of Bach essences in the treatment of fears and traumas in children who live in a poor situation. This is a randomized clinical trial, double-blind, with quantitative and qualitative approach. The children and the art therapist expert, who will analyze the fear and trauma won’t know who integrates each group. The research will be carried out in the non-governmental organization called “Gotas de Flor com Amor”. There are 17 children, between 6 and 8 years old, that will be participating and the group will be divided in two: experimental and placebo. The first group will receive the flower essences for fear and trauma: Rock Rose, Mimulus, Aspen, Star of Bethlehem and the second group will receive only water. The intervention will last 60 days. The effect of the Flower essences will be analysed quantitatively and qualitatively by an expert through the creation of a garden using the principles of art therapy in 3 different moments: In the beginning, in the middle and in the end of the study. This project was approved by the research ethic board from Sao Paulo University Nursering School. The meeting with the children’s parents has already been held in order to explain them the research and to get their approval and signature of the Consent Form.

Biography:

Leia Fortes Salles, RN, PhD is a Post doctorated from the Nursing School - University of Sao Paulo, Brazil. She is specializing in Integrative Medicine, Iridology and Flower Therapy. She is a member of the group of complementary and alternative therapies studies -National Research Council.

Abstract:

The aim of this study was to compare the development of diabetes mellitus in subjects with and without the sign of the Cross of Andreas in the iris over a period of four years. Participated in this cohort study was 91 patients without the disease, with and without the signal. The monitoring was conducted by means of the records. At the end of the research, 28.2% of the group with the sign of the Cross of Andreas was diagnosed with diabetes and 56.5% had two or more episodes of impaired glucose tolerance. In the group without the signal, 4.4% were diagnosed with the disease and 24.5% had two or more episodes of glucose intolerance. There was a statistically significant difference between the groups regarding the development of the disease and glucose intolerance. The group with the Cross of Andreas developed more glucose intolerance and diabetes than the other group.

Biography:

O S Awotunde has completed his MSc from University of Ilorin and is presently doing his PhD at Ladoke Akintola University of Technology, Ogbomoso Nigeria. He is presently a Lecturer at Habib Medical School, IUIU Kampala Uganda. He has presented papers at many conferences in Nigeria, Uganda and India. He is co-author of a published paper in reputed journal and has a published paper and 2 published abstract papers. He teaches Biochemistry and serves as Departmental Tutorial Head.

Abstract:

The aqueous extract of Massularia acuminate root a plant with androgenic potentials at the doses of 50, 100 and 200 mg/kg body weight was investigated for its toxicological implication on selected enzyme activities, liver function and kidney function parameters in vivo and In vitro in male Wistar rats. Phytochemical screening reveals the presence of alkaloids, anthraquinones, saponins, phenolics, flavonoids and tannins in the extract. It caused labilization in some organs whereas it induced the synthesis of enzymes in some others by the increase and decrease (p<0.05) in the activities of alkaline phosphatase, acid phosphatase and gamma-glutamyl transferase. There was increase (p<0.05) in serum total and conjugated bilirubin, increase (p<0.05) in serum globulin and serum albumin at the highest dose of 200 mg/kg body weight. A significant increase (p<0.05) in sodium and potassium ions at various doses following the administration of the extract was revealed. Also an increase (p<0.05) in potassium and calcium ions occurred after day 7 following the administration of the extract at the doses of 100 and 200 mg/kg body weight. The serum urea and creatinine increased at all doses. Therefore, such alterations in the normal levels of the liver and kidney function indices, and tissue enzymes might adversely affect the normal functioning of the biomolecules and by extension, the organs.

Biography:

Duquesne Marilyn has completed her master thesis at the University of Mons (UMONS) on a subject related to the Balkan Endemic Nephropathy, and obtained a PhD grant on which she is currently working. The result acquired during the master thesis has been published. This funding is co-funded by Joelle Nortier, Head of the department of dialysis and kidney transplantation at Erasme Hospital in Belgium, and Jean-Marie Colet, Head of the Human Biology & Toxicology laboratory at UMONS. This collaboration, already initiated during my master thesis, now includes the Nephrology Department of Zagreb University Hospital headed by Bojan Jelakovic.

Abstract:

Aristolochic acid (AA) produced by some plants from the Aristolochia genus, Asarum and Bragantia species, is a common term to define the mixture of structurally related nitrophenantrene carboxylic acid derivatives. AA-I and AA-II are the major components of such mixtures and are structurally similar except for the presence of an0-methoxy group on AA-I. Various Aristolochia species are used in traditional medicines for the treatment of diverse disorders like snakebites, fever, gout, infection, diarrhea, arthritis, rheumatism. Due to severe adverse effects, including urothelial cancers and renal deficiency, encountered in self-medicating patients, Aristolochia-based remedies are nowadays forbidden in Europe and in the United States. On the contrary, those plants are still commonly used as herbal remedies in Iran, India, Bangladesh and many other parts of the world. Rat models of acute and chronic AAI and/or AAII-induced toxicity have been developed and described in the literature. Due to the renal organotropism of AA toxicities, our laboratory was interested in studying the urinary metabonomic profiles of rats exposed to those toxicants. This new “omic” concept allowed to identify which part of the kidney is mostly affected, the toxic mode of action and to discover potential urine biomarkers of the pathology.

Biography:

Fikile Vilakazi has more than 18 years of work experience. She has been working in the fields of youth, women, gender, entrepreneurship development, and sexuality at different times in all these years. Her areas of focus included training, public education and advocacy. She had an opportunity to do student support and mentoring, field work, outreach programs, community mobilization, and building partnerships, manage and direct programs. She has six years of that period dedicated to fundraising, directing an organization, providing strategic direction to processes, organizational development including human, financial and technical resource management, monitoring and evaluation. Her experience has mainly been with student movements, community based and non-governmental organizations, coalitions and local government. In that time she has been exposed to different approaches and paradigms namely (1) integrated approach to development, (2) human rights based approach, (3) gender mainstreaming, (4) feminist approach and ideology. He/She is currently pursuing a Doctoral degree majoring in social and public policy with the University of Jyvaskyla in Finland.

Abstract:

Public participation in the development of regulation/legislation has gained increased prominence within the international research community, inspiring some theorists and policy-makers to talk of a ‘new paradigm’ for research and many organizations to review and reform their research programmes and practices. Although much is known about African traditional medicines, there are still many unanswered questions about its regulation. Ensuring broader public participation can have a real impact on the promotion and authentication of anecdotal knowledge of African traditional medicines throughout the world. This can change the ways in which government or concerned organizations think and act while dealing with the development of African traditional medicines regulation. This research was aimed at measuring the level of public participation and the role of trust and reciprocity amongst African Traditional Health Practitioners (ATHPs) from the Thembisile Hani Local Municipality in the regulation of African Traditional Medicines (ATMs) in South Africa. A quantitative research methodology was employed throughout the research process and data collected using self-administered questionnaires. The results indicate that reciprocity and trust play a statistically significant role (P>|t| value of 0.00 in reciprocity and 0.01 in trust) to influence levels of participation. In addition high levels of trust in government (62%) by ATHPs correlated with ATHPs decreased levels of participation in the current regulation of ATMs by government.

Biography:

Bushra Ahmad has recently submitted her PhD thesis. She has worked for six months at University of Oxford as visiting research student to conduct a part of her PhD research. She has published 10 papers in reputed journals.

Abstract:

Dicliptera roxburghiana (Acanthaceae) is used as general tonic and for wound healing in traditional medicine system of Pakistan. This research project was designed to investigate the nephroprotective effects of methanol extract of D. roxburghiana (DRME) on CCl4 induced renaltoxicity in mice. Balb c mice (42) were treated with their respective doses for 30 days. Group 1 was control group. Group II was administered with DMSO and olive oil. Group III was treated with CCl4 (1 ml/kg b.w; 20% in olive oil). Group IV was administered with CCl4 and Silymarin (50 mg/kg). Group V and VI were administered with CCl4 and DRME 40 and 60 mg/ kg b.w. respectively. Group VII received DRME 60 mg/kg b.w. urine profile showed low pH, decreased level of urine proteins whereas elevated levels of specific gravity, red and white blood cells and urea in CCl4 treated group. Serum analysis revealed decreased overall proteins, albumin and globulin whereas elevated creatinine, urobilinogen and bilirubin levels in CCl4 intoxicated mice. Antioxidant enzymese Catalase, Peroxidase, Superoxide dismutase, Glutathione-S-transferaseand Glutathione reductase were low whereas γ-GT was high in kidney of CCl4 treated group. Furthermore, decreased GSH contents and total tissue proteins while elevated TBARS contents and damaged DNA were noticed in CCl4 intoxicated kidney. Renal histoarchitecture showed cellular infiltration, glomerular atrophy, dilated tubules and damaged Bowman’s capsule in CCl4 intoxicated mice. These anomalies were reversed by DRME doses. On the basis of our results obtained in this study, we suggest the protective role of D. roxburghiana in renal toxicity.

Biography:

Dongshuo is currently a PhD student in Health Research at Lancaster University. She received Traditional Chinese Medicine (TCM) training in Fujian TCM University, and BA in intercultural communication and MSc in Research Methodology at the University of Manchester. She is the Co-founder of the TCM Clinic at the University of Manchester where staff and students with stress can be treated. She has been researching and developing TCM in the west, and has given talks in China Academy of Chinese Medical Sciences, Oxford University, and Manchester University etc., and has published a dozen papers in journals and as book chapters.

Abstract:

This study explored Chinese international students’ perceptions of health and wellbeing in relation to the attitude towards and use of Traditional Chinese Medicine (TCM). The perceptions were identified from three aspects: social perceptions concerning with individuals’ daily interactions with others; environmental perceptions dealing with individuals functioning effectively in their physical environment; and psychological perceptions centring round individual characteristics related to a person’s well-being in society. The qualitative data from individual and focus group interviews in this study revealed that Confucianism has greatly shaped the social and psychological perceptions and the way in which health, wellbeing, and treatment are conceptualised and practiced. Taoism dominates environmental perceptions of health and wellbeing with the theory of naturalism, emphasizing the impact of environmental factors on disease. Data analysis illustrated that the reasons that Chinese international students used TCM to cope with the adjustments are: problems that cannot be cured in Western medicine (WM), recommendation from friends and relatives, habitual action inherited from families and being familiar with the Chinese approach to illness. The reasons for not using TCM are listed as the high cost, lack of information about TCM clinics, inconsistency of practitioners’ professional levels, the length of curing illness, the inconvenience to consume the herbs and disclosure of clinical secrets. These factors are discussed with reference to literature review, and suggestions and recommendations are put forward.