Jong-Cheng Mou has completed his PhD and Postdoctoral studies in College of Korean Medicine, Semyung University. He majored in Korean Medicine and published several papers in reputed journals. After graduation, he manages the clinic of Korean Medicine in Korea. He has taught Korean Medicine to students in College of Korean Medicine, Semyung University.
Hemorrhoids are one of the most common diseases in humans. About half of the people older than age 50 years have symptomatic hemorrhoids. Swelling and inflammation are typical hemorrhoid symptoms. In Traditional Korean Medicine, Jingyoganghwaltang and Cheongsimhwan have been used to treat diseases in anal fistula. Cheongsimhwan reduces a fever and has anti-inflammatory effects. This study investigated the effect of a mixture of Jingyoganghwaltang and Cheongsimhwan on croton oil induced hemorrhoid model in rats. Male rats aged 6 weeks were divided into three groups: Control, Croton oil stimulated group, and drug (a mixture of Jingyoganghwaltang and Cheongsimhwan) treated group. After three days of drug treatment, the animals except the control group were stimulated for 60 seconds by inserting the croton oil mixture (DW:pyridine:diethyl ether:6% of croton oil in diethyl ether = 1:4:5:10) into the anus. After 4 hours, all rats were sacrificed under deep anesthesia, and retro-anal tissue was excised for histological, immunohistochemical analysis and western blotting. The weight of retro-anal tissue of the drug treated group was decreased to 86.4±2.9% (compared to 100% of the croton oil treated group). In a histological study of rectro-anal sections, severe inflammation can be observed in the croton oil treated group, and the drug treated group showed the reduction of inflammation. Additionally, the drug treated group showed the decrease in contents of ICAM1, MMP2 and MMP9 compared to the croton oil stimulated group. These results suggest that the treatment with Jingyoganghwaltang and Cheongsimhwan demonstrates the anti-inflammatory effects in croton oil induced hemorrhoid model in rats.
Fangfang Mo has completed her M.D. in 2012 from Beijing University of Chinese Medicine(BUCM), School of Basic Medical Sciences with Prof. Sihua Gao as her teacher. In the same year, she became a lecturer in BUCM. And she is working on research of correlation between zang and fu organs in TCM and diabetes prevention and treatment with chinese herbs based on integrating Chinese medicine with modern medicine. She has published more than 10 papers in journals.
Diabetes is the syndrome of sugar, protein, fat, water and electrolyte metabolic disorder that occurs when the body cannot produce enough or effectively use insulin. And it can be assigned to Emaciation-Thirst Disease in Traditional Chinese Medicine (TCM). According to the basic understanding of TCM and pathophysiological knowledge of western medicine, it can be found that pathogenesis of type 2 diabetes mellitus (T2DM) is the combination of protective qi deficiency, dampness and phlegm, blood stasis and inner heat due to disorders of liver, spleen and kidney function. Based on the characteristic of pathogenesis, Prof. Sihua Gao puts forward the conception of “treatment for T2DM by regulating liver, spleen and kidney together”, and prescribes three formulas of Chinese herbs which are named jiangtangxiaoke formula I, formula II, and formula III. All of the above prescriptions have good clinical efficacy. Furthermore, jiangtangxiaoke formula I used should be nourishing kidney, supplemented by tonifying spleen soothing liver, reinforcing both qi and yin, and activating blood. Jiangtangxiaoke formula II used should be soothing liver, supplemented by tonifying spleen nourishing kidney, regulating qi and clearing heat. Jiangtangxiaoke formula III used should be tonifying spleen, supplemented by soothing liver nourishing kidney, reinforcing qi and removing dampness. Meanwhile, Prof. Gao proposes the whole thinking of T2DM prevention. A series of specific methods are presented, such as self-psychological adjustment, reasonable dietary habit, appropriate exercise program and choosing the right music. And the aim is to tonify spleen, soothe liver and nourish kidney. Thus it can be seen that “treatment for T2DM by regulating liver, spleen and kidney together” integrates Chinese medicine with modern medicine. And this idea enriches scientific basis of TCM, offers a new thought for understanding the mechanism, and plays an important role in diagnosis, prevention and control, treatment as well as development of effective drugs for T2DM.