6^th International Conference and Exhibition on Traditional & Alternative Medicine September 14-16, 2016 Amsterdam, Netherlands

Biography:

Yibin Feng is currently an Associate Professor cum Associate Director in the School of Chinese Medicine, The University of Hong Kong. He completed his Bachelor’s degree in Chinese Medicine from Mainland China, PhD in Molecular Medicine from Hokkaido University School of Medicine and finished Post-doctoral research in the same University in Japan. His research interest focuses on clinical trial and experimental study for cancer, diabetes, hepatic and renal diseases by using recently developed techniques. He has published over 200 publications in these areas and serve as an editor and reviewer for many international journals.

Abstract:

Chinese medicine has its own science and art. To understand Chinese medicine on scientific basis and to push Chinese medicine has become a part of world medical system. Bioscience and OMICS technologies are powerful approaches in Chinese medicine research. In the past years, drug discovery from Chinese medicines have been acknowledged worldwide, such as artemisinin for antimalarial and arsenic trioxide for treatment of acute promyelocytic leukemia. Actually, as a complementary and alternative medicine, Chinese medicine rarely uses single pure compound or single herb, instead, it always uses blend of several herbs (composite formulae, or Fufang in Chinese) to treat diseases. One of the unique advantages in Chinese medicine is that it can use known Chinese medicinal herbs to create new composite formulae for new diseases such as SARS, new type influenza and other chronic diseases. Facing complicated diseases, Western medicine have been also using combination therapy in modern medical practice, such as “cocktail therapy” for AIDS, combination chemotherapy for cancer. Identification of natural origin, quality control, gut bacteria metabolite, pharmacological effects, molecular targets and clinical trial which are caried out on international platform should be emphasized. Some successful cases will be used as paradigms to illustrate this approach on study of Chinese medicines in in vitro and in vivo, in this presentation.

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Sumita Satarkar Founder and Head of the management Saheacci School of Alternative healing and Acupuncture Insync Pune, India.& Founder Director Swasthya Santulan Pvt.Ltd She has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. She has extended his/her valuable service towards the scientific community with her extensive research work.

Abstract:

‘Acupuncture’ an age old science, also known as an alternative healing technique, is mostly used for prevention of disease to maintain the balance of life. The practice of Acupuncture consists of either stimulation or dispersion of the flow of vital energy within the body by inserting needles into specific points on the body surface, applying heat [moxibustion], or by pressing points [Acupressure]. Pulse is one of the most important diagnostic tool used from ancient times, which needs accuracy and focus. Unlike any other faculty of medicine, this age old science of alternative healing is a study of ‘energy’ which neither can be measured nor be seen .It can only be palpated at the wrist. Palpation and its interpretation bring forth the detail analysis of energy and its patterns and thus further can be accurately diagnose the exact illness or disorder. This is called a ‘’ Pulse diagnosis.’’ Pulse provides valuable clinical information which can be used to gain a deep understanding of the patient’s illness or symptoms on many levels. It warns the patient of the forthcoming illnesses, indicating the present and also the damage done in the past in the body, if the acupuncturist knows the method perfectly.

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Mara Doljak has completed her Master’s degree in Pharmacy. She is the Founder and Owner of a certified Aromatherapy school (Aroma Center) and a company (Aromara) that promotes aromatherapy and aromatherapy products intended for health and beauty. In 2015, she held lectures at the following conferences: Phyt’Arom Grasse in France, Pacific Institute of Aromatherapy in San Francisco, USA and International Conference on Natural Products Utilization in Plovdiv, Bulgaria.

Abstract:

Croatia is a marvellous country but in a post-war aftermath with deep economic, moral and intellectual consequences. Since 1991, we at Aromara have been spreading awareness about aromatherapy through education, products and impact at a Governmental level. When researching product development, we seek common chronic health problems that lack an effective pharmacological cure. This is the case for vaginal infections. Most common forms of vaginitis are bacterial vaginosis (40-45%), vaginal candidiasis (20-25%) and trichomoniasis (15-20%). Up to 70% of women may remain undiagnosed. 498 million people aged 15 to 49 worldwide are infected each year with chlamydia, gonorrhea, syphilis or trichomoniasis. A synergistic combination of Helianthus annuus, Hypericum perforatum, Calendula officinalis, Prunus armeniaca fixed oils and Melaleuca alternifolia, Cymbopogon martinii, Cananga odorata, Helichrysum italicum, Pogostemon patchouli, Pelargonium graveolens and Matricaria chamomilla essential oils, used daily, showed results in alleviating symptoms and providing clear medical tests of the vaginal flora. Aromatograms and pharmacological properties of the main ingredients demonstrate the health benefits of the formulation. The sociological results of improving women's vaginal health are higher creativity, less depression, better overall health, better sexual life, better motherhood, healthier family - the results of which brings us towards promoting a healthy society.

Biography:

Y L Gong has completed his PhD in Gastroenterology from 2nd Military Medical University of Shanghai in the year 1997. Currently, he is working as a specialist in the Department of Oncology, Nanjing 1st Hospital, and Nanjing Medical University, China. He has published more than 40 scientific papers in various national and international journals and a reviewer for reputed journals. Apart from medical oncology, his area of interest is Chinese traditional medicine therapy of hepatic cell carcinoma.

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Aim： The main of the study is to contribute a humble effort to promote Chinese traditional medicine, a retrospective clinical study was performed to assess the efficacy of Chinese herbal decoction-based combination treatment of hepatic cell carcinoma (HCC). Methods：42 hospitalized patients with histologically confirmed HCC from Jan 2012 to Dec 2014 were selected randomly, including 22 cases in the control group for conventional therapy of surgical resection and/or chemo-radiotherapy as usual; and 20 patients in the study group for combined treatment of “warm and removing” decoction (WRD) on the basis of standard care. In the meantime, evaluation of clinical characteristics and quality of life was assessed. Results: There was a significant difference (P<0.05) in the comparison of AFP (alpha feto protein)/ALT (alanine transaminase) level between control and study groups. The DCR (disease control rate） was 43% in the study group compared with 34% in the control group. Three-month PFS (Progression-Free-Survival) and TTP (Time-to-Progression) rates were 60%, 35% for WRD patients and 45%, 40% for control patients, respectively. The retrospective clinical study showed no overall survival (OS) benefit for HCC patients treated with WRD compared with control, while the QOL (quality of life) evaluation seemed to predict survival better for WRD patients than that for control patients. Conclusions: Chinese herbs in the WRD may have the ability of increasing cellular immunity and reducing surgical or chemo-radio-therapeutic lesions. Chinese herbs of WRD might be an additional choice with its better benefits and tolerability in the combination treatment of HCC.

Biography:

Gehan Moustafa Badr has completed her PhD from Ain Shams University. She is lectureur in Science college Ain Shams University from 2007, and currently, she works in Science College, King Faisal University in girls sections from 2007 till now. She has published two papers about alternative medicine against gastric ulcers and hepatotoxicity. She gets funds for two projects from King Faisal University. She research papers which published or under press are on Aged garlic extract, Parsly oil, Green tea, proplis and Myrrah plants

Abstract:

Aged Garlic Extract (AGE) exhibit a significant anti inflammatory effect in numerous diseases. However, the anti inflammatory effects of AGE in arthritic conditions not well documented and the Methotrexate (MTX) is an anchor drug used to treat rheumatoid arthritis (RA), but responsiveness is variable in effectiveness and hepatotoxicity in healthy and collagen-induced arthritis (CIA)-rats. Therefore, the present study used adult female rats divided into 8 groups of rats: Control healthy, CIA, CIA treated with AGE and/or MTX, healthy treated with AGE and/or MTX. Arthritis induced by intradermally injection of collagen complete Freund's adjuvant (CFA) emulsion (4 mg/kg)at the base of the tail in each rat. All treatments started once the peak symptoms of arthritis appeared (20th day). AGE treatment (from day 21 to 50) 200 mg/kg/PO. CIA-rats injected by subcutaneous dose of 1.5 mg/kg per 2 days of MTX from day 21 to 43. Efficacy of AGE alone or combined with the medicine was assessed based on the ability to reduce paw oedema, histopathological changes, reduction of the liver enzyme activities and oxidative parameters, elevation of hepatic antioxidant enzymes, arthritis-induced changes in body weight, C-reactive protein (CRP), Serum Tumour Necrosis Factor (TNF) α and interleukin (IL)-17 levels. The study aimed to evaluate the anti-inflammatory effect in CIA-rats of AGE alone and its synergetic activity in combination treatment with methotrexate and its protection against methotrexate induce toxicity.

Biography:

Heshu Sulaiman Rahman has completed her PhD from University Putra Malaysia. She is the Director of Laboratory Research Center, College of Veterinary Medicine, University of Sulaimani, Northern Iraq. She has published more than 35 papers in reputed journals and has been serving as an Editorial Board Member of repute. She was awarded with more than 10 medals, 10 appreciation letters, and owned 6 patents.

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The current study investigated the anticancer properties of gold nanoparticles (SG-stabilized AuNPs) synthesized using water extracts of the brown seaweed Sargassum glaucescens (SG). SG-stabilized AuNPs were characterized by ultraviolet-visible spectroscopy, transmission and scanning electron microscopy, and energy dispersive X-ray fluorescence spectrometry. The SG-stabilized AuNPs were stable and small at 3.65±1.69 nm in size. The in vitro anticancer effect of SG-stabilized AuNPs was determined on cervical (HeLa), liver (HepG2), breast (MDA-MB-231) and leukemia (CEM-ss) cell lines using fluorescent microscopy, flow cytometry, and caspase activity determination, and MTT assay. After 72 hours treatment, SG-stabilized AuNPs was shown to be significantly (P<0.05) cytotoxic to the cancer cells in dose- and time-dependent manner. The IC50 of SG-stabilized AuNPs on HeLa, HepG2, CEM-ss, MDA-MB-231 cell lines were 4.75±1.23, 7.14±1.45, 10.32±1.5, and 11.82±0.9 μg/mL, respectively. On the other hand, SG-stabilized AuNPs showed no cytotoxic effect towards the normal human mammary epithelial cells (MCF-10A). SG-stabilized AuNPs significantly (P<0.05) arrest HeLa cell cycle at G2/M phase and significantly (P<0.05) activated caspases-3 and -9 activities. The anticancer effect of SG-stabilized AuNPs is via the intrinsic apoptotic pathway. The study showed that SG-stabilized AuNPs is a good candidate to be developed into a chemotherapeutic compound for the treatment of cancers especially cervical cancer.

Biography:

Mthokozisi B C Simelane has completed his PhD from University of Zululand in the Department of Biochemistry and Microbiology. He is working as a Lecturer of Biochemistry at the University of KwaZulu-Natal. He has published more than 6 papers in reputed journals and has been serving as a reviewer to different journals.

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Despite the various efforts by governmental and non-governmental organizations aimed at eradicating the disease, malaria is said to kill a child every 30 seconds. Traditional healers use different concoctions prepared from medicinal plants to treat malaria. In the quest to bio-prospect plant-derived triterpenes for anti-malaria activity, we report here the in vivo antiplasmodial activity of Ursolic acid acetate (Ursolic acid isolated from dichloromethane extract of Mimusops caffra was chemically modified to its acetate derivative). The transdermal administration of Ursolic acid acetate (UAA) dose dependently showed complete inhibition of the parasites’ growth at the highest concentration of 400 mg/kg after 15 days of Plasmodium berghei infection. UAA prevented the in vitro aggregation of MDH but did not prevent the expression of PfHsp 70 in E. coli XL1 blue cells. It, however, enhanced PfHsp70 ATPase activity with the specific activity of 65 units (amount of phosphate released 73.83 nmolPi/min.mg). Ursolic acid acetate prevented the formation of hemozoin (60±0.02% at 6 mg/ml). The results suggest that Ursolic acid acetate possesses potential anti-malaria properties.

Biography:

Olugbenga Morebise obtained a PhD degree in Biochemistry from the University of Ibadan, Ibadan, Nigeria. He has been involved in both teaching and research in Nigeria before moving to the Caribbean. He currently teaches Biochemistry at the All Saints University School of Medicine, Roseau, Dominica. He has done his research work on bioactivities of medicinal plants, including anti-inflammatory, analgesic, antimicrobial, anti-diabetic and allelopathic activities. He has published articles in reputable journals. He currently hopes to team up with his colleagues to establish a phytochemical/ herbal research unit in Dominica.

Abstract:

Dominica, the nature isle of the Caribbean, is a country whose citizens are noted for growing old gracefully and living long healthily. The country has been reported to have the highest percentage of centenarians per capita in the world. This is attributed to the wide consumption of natural products which include herbal medicines and cultivated vegetables and fruits. Bush tea is a common term in Dominica and it refers to the decoction, concoction or infusion made from the medicinal plants. This presentation shows how the popular medicinal plants are usually used by the locals in Dominica and their strong folkloric beliefs on the efficacies of the herbals. The chemical composition of the plants and bioactivity reports on them, based on research finding from different parts of the world, are also presented in this report. Some of the plants still have few or no phytochemical and bioactivity reports on them, indicating ideal areas for novel researches. Future prospects and recommendations in the areas of novel herbal formulations, drug discovery and medicinal plant research in Dominica are also highlighted.

Biography:

Ajibola Ola Peters completed the National Certificate of Education (NCE) and obtained the Ordinary National Diploma (OND) in 1991. Thereafter, he fully joined his family’s hereditary herbal medicine healthcare home as one of the herbalist. Currently, he is the Managing Director of Natural Herbal Solutions Common Initiative Group - (PONAS C.I.G). He is the Author of the popular medicinal plants book titled Herbs, Health and Diseases, published in 2007. He is also an herbal hospital practitioner.

Abstract:

The major challenge of traditional herbal medicine is the availability, which is under serious threat. Over 90% of the medicinal plants used by the traditional doctors and industries worldwide today are collected from the wild. 10% species of plants are under commercial cultivation. Over 80 % of the plant collections involve destructive harvesting by timber exploiter companies and traditional doctors because of the use of parts like roots, bark, stem, leaf and in some cases, the whole plant. This shows a definite threat and challenge to the genetic stocks and to the diversity of medicinal plants as well as the need for conservation and cultivation of endangered species. Presently, 85% of the world population is using and relies on medicinal plant medication for common and emerging diseases. The majority of pharmaceutical processing companies have also diverted their focus to selected effective medicinal plants formulae for re-production because they foresee that in future, 95% of the whole world will prefer natural herbal medication because of their prominent role in treating existing and emerging diseases. There has been a serious investment in herbal medicine and research by public-health bodies in many countries including China, South Africa and USA. In 2004, the National Cancer Institute committed nearly US$ 89 million to study a range of traditional therapies. In recent years, more than $2 billion has been committed by public- health bodies. The growing investment and worldwide faith in its consumption has shown that the future direction of traditional herbal medicine will soon be the world’s popular choice.